IVF Update: Follistim, Menopur, Ganirelix

I started Menopur and Follistim shots on Monday, so I am going on day eight of those now! I had an appointment at GRS Thursday morning, where an ultrasound revealed that I had seventeen follicles on my right ovary and twelve on my left. They were all very small still. My estrogen level was 156.

Since I was still having some bleeding (Thursday was day eight of bleeding, which is super weird for me), they decided to up my dosage of Follistim from 75 to 100. So from Thursday to Saturday, I took that increased dosage of Follistim, and 75 IU of Menopur.

Saturday morning I went back to GRS for more bloodwork. I had fewer follicles than I did at Thursday’s appointment, but they were bigger (although they still had a ways to go). My uterine lining had also doubled in thickness, which was a relief, since thin lining has been an issue for me in the past. It was only six and a half mm thick, and needs to be between eight and thirteen, but I have several days to work on thickening it up some. My estrogen level was 360 when they checked in Saturday.

The doctor on call over the weekend told me to avoid using scented products on my skin: lotions, body wash, body sprays, etc. He said there have been studies done that indicate that scented products are not good for egg quality.

After the results from Saturday’s blood work, I was again instructed to increase my dosage of Follistim, going from 100 to 150. And I started Ganirelix injections tonight (Sunday). The prep work for Ganirelix is easier than Follistim and Menopur, since the Ganirelix is already mixed

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and ready to go, but for some reason the actual giving of the Ganirelix shot is a bit more difficult than the Menopur or Follistim. The needle seems to want to bounce off the skin!

The Follistim is a very easy shot to give. The needle is teensy, and I barely feel it. The Menopur is not a difficult shot to give, but the medicine does sting a bit going in. The Ganirelix does not sting going in, and is easy once I get the needle through the skin. But the Ganirelix injection site stings after the fact for a while. Nothing major or debilitating though!

My tummy is a bit bruised. The nurse suggested that I give one of the three shots in my thigh, but the thought freaks me out. I have more padding on my tummy than my thigh… it’s about time that stuff comes in handy! (: I am sticking to the tummy for all three shots.

In addition to being a little bruised, my stomach is pretty swollen and tender. Not from the shots, but because of my ovaries. The doctor told me that I could expect some bloating and fullness as my ovaries get bigger and bigger and bigger. They seriously feel huge!

Here is a quick overview of each shot’s purpose:

Follistim- It is a recombinant follicle stimulating hormone that helps healthy ovaries to develop and release mature eggs.

Menopur- Menopur injection contains human menopausal gonadotrophin as the active ingredient. Human menopausal gonadotrophin is a combination of two naturally-occurring female hormones, follicle stimulating hormone (FSH) and luteinising hormone (LH), extracted and purified from the urine of post-menopausal women. In the case of IVF, Menopur is used to stimulate multiple follicles and eggs to develop.

Ganirelix- This prevents ovulation, so that we do not loose precious eggs before the egg retrieval. It allows the doctors to time ovulation more accurately.

My next appointment is Tuesday. After that appointment, we should be able to have a pretty clear idea of when our egg retrieval will be! I can’t believe it’s almost time!

I would say that I am excited, but that is SUCH an understatement!




  1. 1

    Natalia says

    Hi Logan!

    I’m so excited for you!!! I’m keeping you in my prayers and hope this time you receive wonderful news!

    I’m so thankful for all the information you’ve posted. I know it will help me when DH and I decide to have a baby!

    Keep posting. I read your blog everyday! It has become one of my favorites…

    *virtual hugs your way*

    • 2

      leandreotta@gmail.comleandreotta@gmail.com says

      Thank you so much Natalia! It is so nice to hear such positive feedback, and to know the blog is a help to someone!

      I hope you have a wonderful week!


  2. 3

    amywales121 says

    Logan! You are so brave! I love hearing how hopeful you and your husband are together! Your posts are always so informative and I know if Alex and I decide to do IVF I will return to your blog first thing as a reference! Praying for you daily!

    • 5

      LoganLogan says

      Praying hard. Please keep me posted on your results… I would tell you to enjoy you two-week wait, but I know that’s next to impossible! (:


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